New study finds CD4 T-Cell and Blimp-1 protein critical to toxoplasmosis regulation

New research critical to treatment for chronic toxoplasmosis, one of the most common parasitic diseases worldwide, was published in the Journal of Experimental Medicine. Researchers from the George Washington University (GW) uncovered a connection between CD8 T-cell exhaustion and CD4 T-cell exhaustion, not found before. They also discovered that CD4 T-cells can be regulated by Blimp-1 protein expression. Through regulating CD4 T-cells, CD8 T-cells can be regulated, which could lead to new therapeutic possibilities.