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France to tighten up drug trial rules after fatal incident

France's health minister presented a plan on Monday to tighten the rules regarding human drug trials following an experimental test that killed a volunteer in January.

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FDA delay raises slim hope for muscular dystrophy drug

Federal health regulators will take more time to review a highly-contested drug for muscular dystrophy that has become a flashpoint in the debate over patient access to experimental medicine.

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A combined approach to treating metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues...

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Shift work unwinds body clocks, leading to more severe strokes

Statistics show that some 15 million Americans don't work the typical nine-to-five. These employees (or shift workers), who punch in for graveyard or rotating shifts, are more prone to numerous health...

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Investigational immunotherapy drug shrinks tumors in high-risk neuroblastoma...

Neuroblastoma tumors shrank, some dramatically, in 80 percent of newly diagnosed, young, high-risk patients enrolled in a Phase II clinical trial that included an experimental monoclonal antibody. The...

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Combination therapy cures tick-borne illness in mice

A novel combination therapy cures an emerging infectious disease, babesiosis, which is transmitted by the same ticks that transmit the agents of Lyme disease, said Yale researchers. This "radical"...

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Fat tissue shows a robust circadian rhythm in a dish

In humans, glucose tolerance varies with time of day, but the mechanism responsible for the variation in insulin sensitivity throughout the day is unclear. In a recent study in The Journal of the...

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Female sex hormone clue to fighting serious immune disease

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2016) showed for the first time a beneficial effect of oestrogens in experimental models of skin...

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Implantable ultrasound device augments chemo in glioblastoma

(HealthDay)—An implantable ultrasound device (SonoCloud) appears to enhance chemotherapy treatment in glioblastoma, according to research published online June 15 in Science Translational Medicine.

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Experimental Zika vaccine to begin human testing

An experimental vaccine for the Zika virus is due to begin human testing in coming weeks, after getting the green light from U.S. health officials.

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Compound shown to reduce brain damage caused by anesthesia in early study

An experimental drug prevented learning deficits in young mice exposed repeatedly to anesthesia, according to a study led by researchers from NYU Langone Medical Center and published June 22 in Science...

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Malaria vaccine loses effectiveness over several years: study

An experimental vaccine against malaria known as Mosquirix—or RTS,S—weakens over time and is only about four percent effective over a seven-year span, researchers said Wednesday.

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Study of promising cancer treatment allowed to resume

A study of an experimental treatment for leukemia that was halted last week following two patient deaths has been allowed to resume after a modification.

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NIH launches early-stage yellow fever vaccine trial

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has begun an early-stage clinical trial of an investigational vaccine designed to...

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New study finds CD4 T-Cell and Blimp-1 protein critical to toxoplasmosis...

New research critical to treatment for chronic toxoplasmosis, one of the most common parasitic diseases worldwide, was published in the Journal of Experimental Medicine. Researchers from the George...

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NIH begins testing investigational Zika vaccine in humans

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched a clinical trial of a vaccine candidate intended to prevent Zika virus...

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Psychologist's magic makes a non-existent object disappear

Magicians use sleight of hand to confuse you about where an object is. But could they make you believe that you saw a non-existent object disappear?

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Greater intake of dietary omega-3 fatty acids associated with lower risk of...

In middle-aged and older individuals with type 2 diabetes, intake of at least 500 mg/d of dietary long-chain ω-3 polyunsaturated fatty acids, easily achievable with 2 weekly servings of oily fish, was...

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Volunteers sought as race to develop a Zika vaccine heats up

Wanted: Volunteers willing to be infected with the Zika virus for science.

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Psychologists see humor as a character strength

Humor is observed in all cultures and at all ages. But only in recent decades has experimental psychology respected it as an essential, fundamental human behavior.

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